The Effect of Radiotherapy and Chemotherapy on Some Kidney and Liver Functions in Colorectal Cancer Patients

Abstract

The current study was conducted in Al-Diwania Teaching Hospital/Oncology Division and Middle Furat
Center for Cancerous Tumors in Al-Najaf, Babil Health Department/Marjan Hospital, Babil Health
Department/Imam Al-Sadiq Hospital and Medical City Department/Al-Amal Hospital for the treatment
of tumors and continued for the period from 2/10/2019 6/5/2020 60 samples were taken from patients
diagnosed with colorectal cancer and 30 samples from non-infected people as a control group, with ages
ranging from 33 years to 80 years for both groups . The results showed an increase in the level of Creatinine
in the patient group compared to the control group and it was the highest in the radiotherapy group, followed
by the chemotherapy group and then the control group. The results showed high significant differences
between the three groups (p <0.001), and there were significant differences between the radiotherapy group.
And a chemotherapy group. Through the results, it was found that the average level of Creatinine increased
in the radiotherapy and chemotherapy groups compared to the control group. The results showed that the
mean of AST was highest in the radiotherapy group, followed by the chemotherapy group and then the
control group. The results showed high significant differences between the three groups (p <0.001). Through
the results, it was found that there were no significant differences between the radiotherapy group and the
chemotherapy group in the average level of the AST enzyme. It was also found that the average level of
AST enzyme was higher for the radiotherapy and chemotherapy groups compared to the control group. The
results of the current study showed the highest mean ALT enzyme in the radiotherapy group, followed by the
chemotherapy group compared to the control group. The results showed high significant differences between
the three groups (p<0.001) and significant differences between the radiotherapy group and the chemotherapy
group. ALT for the radiotherapy and chemotherapy groups compared to the control group.