Genetic Mutation Detection of IL-4 Gene in Patients with Atopic Dermatitis in Iraq Population

Abstract

The aim of this study is to detect mutation in IL4 gene in atopic dermatitis patients in Babylon province,
Iraq. The current study was performed on (50) Samples of patients with atopic dermatitis and 40 samples
represents healthy subjects as control group, their ages ranged between 1-20 years old. The results of the
PCR, with newly designed primers, showed 502bp amplicon as well as there were no mutations detected in
nucleotide sequences for all samples including control. Therefore, when compare the results of identity for
any isolate; it was appeared that there are no differences in nucleotides sequences and atopic dermatitis is
not necessarily associated with IL4 gene mutation.