A Comparative Study of Pulmonary Function Tests Type 2 Diabetes Mellitus and Non-Diabetes
DOI:
https://doi.org/10.37506/ijop.v7i4.95Keywords:
T2DM & Pulmonary Function Test.Abstract
Background
Diabetes Mellitus still remains one of the foremost causes of Morbidity and Mortality in both the developing and developed nations. Diabetes Mellitus includes a heterogenous group of hyperglycemic disorders. The presence of extensive microvascular circulation and abundant connective tissue in lungs, raises the possibility that lung tissue could be a target organ in Type2 Diabetes Mellitus
Objective
To study the effects of Type 2 Diabetes Mellitus on lung function tests.
Materials and Method
80 male subjects, 40 Type 2 Diabetes-study group, 40 Healthy-controls selected from Vaishnavi Hospital, Hyderabad. Medspiror instrument was used to record lung functions. Following parameters were recorded: Forced vital capacity (FVC), Forced Expiratory Volume in 1st sec (FEV1), FEV1/FVC ratio, Forced Expiratory Flow in middle half of FVC (FEF 25–75%) and Peak Expiratory Flow Rate (PEF). Statistical analysis was done using unpaired t-test in windows stat 9.2 software.
Results
Study group showed statistically greater percentage reduction in FVC, FEV1, FEF 25–75% and PEF compared to control group.
Conclusion
Type 2 Diabetes Mellitus may be a causative factor for derangement in lung functions due to altered connective tissue, thickening of basal lamina of alveolar membrane and capillary endothelium. All these factors are leading to Restrictive Lung disorder, which exacerbate with increasing blood sugar levels and duration of Type2 Diabetes Mellitus. Therefore lung is considered as a TARGET ORGAN in Type2Diabetes Mellitus.
Downloads
Published
Issue
Section
License
Copyright Ownership: Authors retain copyright ownership of their work after publication in IJOP. However, they grant the journal an exclusive Creative Commons license.
Creative Commons License: The authors grant IJOP the right to exclusively apply a Creative Commons license to their work upon publication. This license permits use, distribution, and reproduction of the work in any medium, provided that the original work and its source are properly cited. The specific license applied is Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0), which allows for attribution, non-commercial use, and derivative works.
Editorial Research: Authors grant the journal the right to analyze information obtained from submitted manuscripts for editorial research purposes. This analysis aims to improve the peer-review process, teaching, and training activities.
Warranties: Authors warrant that their work is original, contains no libelous statements, is lawful, and does not infringe upon any copyright, trademark, patent, or proprietary rights of others. Authors agree to indemnify the editors against any costs, expenses, and damages arising from any breach of this warranty.
Views and Opinions: The views and opinions expressed in the article are those of the authors and not necessarily those of the journal.