Visual Evoked Potential in Diabetics – A Non-invasive Study
DOI:
https://doi.org/10.37506/ijop.v7i1.258Keywords:
Diabetes mellitus, vision, visual evoked potential (VEP), VEP & duration of diabetes mellitus, VEP & FBS levels, waves N70 & P100.Abstract
Background
Prevalence of diabetes mellitus is increasing worldwide, more commonly due to improved lifestyle changes. It is particularly more common in developing countries. Involvement of peripheral, central & autonomic nervous systems are frequently encountered. Diabetes is associated with visual impairment, which if not detected early, can lead to early disability in patients. Visual evoked potential (VEP) is a non invasive method to assess visual pathway. Present study was done to evaluate impact of diabetes on central nervous system, particularly visual functions.
Aims and Objectives
To analyse visual evoked potential in diabetes and age matched controls.
Materials and Method
60 diabetics (NIDDM and IDDM) attending medical out patient department of Bapuji & Chigateri hospital, Davngere and 60 age matched controls selected randomly from general population were subjected to visual evoked potential. Parameters such as latencies of N70, P100 and N155, peak to peak amplitude of waves N70-P100 and P100-N155 were assessed and analyzed by using unpaired student T test for comparison between cases and controls and one way ANOVA for multiple group comparisons within diabetics based on duration of diabetes and fasting blood sugar levels.
Results
patients with diabetes mellitus have subclinical visual impairment as revealed by impaired visual evoked potential. Diabetics showed delayed latencies and reduced amplitude of various parameters of VEP. There was a positive correlation between prolongation of latencies and duration of diabetes and FBS levels.
Conclusion
present study correlates with earlier findings that visual pathway gets involved in diabetics even before the development of retinopathy which can be detected using VEP. Meticulous control of blood sugar levels is a must to prevent complications of diabetes, so that further damage can be prevented.
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