Assessment of Bronchomotor Tone in Normal and Overweight/Obese Normal Subjects
DOI:
https://doi.org/10.37506/ijop.v7i2.187Keywords:
Pulmonary function test, Obesity, .Abstract
Background
Obesity in children and young adults is on a stupendous rise over the last decade globally making the individual highly susceptible to various diseases. Pulmonary functions are well reported complications of obesity in adults with reduced lung volume & expiratory flow rates being the most frequent reported abnormalities.
Methodology
This cross sectional analytical study was undertaken in the research lab of the Department of Physiology, M.K.C.G. Medical College over a period of 12 months on 300 students to determine baseline anthropometric measurements and pulmonary function tests using spirometry. Independent ‘t’ test and multiple linear regression in SPSS 20.0 is used to statistically ascertain the aforementioned objective stated in the background.
Results
VC, ERV, TV, dynamic pulmonary functions; FEV1, MEF25along with PIF and MIF50 showed statistically significant decline in overweight/obese individuals. The aforementioned findings of VC, ERV &FEV1 showed a similar diminished trend in overweight/obese individuals on further evaluation using multiple linear regression analysis.
Conclusion
Overall most of the pulmonary functions tests showed compromised status in overweight/obese individuals with VC, ERV, TV, FEV1, MEF25, PIF and MIF50 exhibiting statistically significant reduction. Mechanistically, this can be attributed to the presence of adipose tissue around the rib cage, in the abdomen and visceral cavity loading the chest wall leading to small airway collapse and subsequent lowering of pulmonary function tests.
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