Impact of Elective Percutaneous Transluminal Coronary Angioplasty (PTCA) on Heart Rate Variability in Patients with Coronary Artery Disease
DOI:
https://doi.org/10.37506/ijop.v8i3.1322Keywords:
Coronary artery disease, heart rate variability, PTCAAbstract
Coronary artery disease (CAD) is a major public health problem in India and is one of the leading causes of
mortality and morbidity. Impairment of heart rate variability (HRV) has been observed in patients with CAD.
Percutaneous transluminal coronary angioplasty (PTCA) is one of the common modalities of treatment of
CAD. In this study we have studied the effect of successful elective PTCA on HRV parameters in patients
with CAD.
Material and Method: HRV parameters in both time and frequency domain were studied in 30 male patients
before PTCA, one day and three day after PTCA.
Results: - The time and frequency domain parameters between pre PTCA and 1st day post PTCA were
not found to be statistically significant. Changes in the time domain parameter rMSSD and SDNN was
statistically significant between pre and 3rd day post PTCA but no significant difference was observed in
pNN50. A significant decrease in LF n.u and increase in HF n.u was observed between pre and 3rd day post
PTCA.
Conclusion: Revascularization with PTCA results in improvement of the autonomic tone. Improved
autonomic modulation is seen as early as 3rd day post PTCA. It indicates that restoring the blood flow
reverses to some extent the autonomic modulatory effect of coronary artery disease.
Downloads
Published
Issue
Section
License
Copyright Ownership: Authors retain copyright ownership of their work after publication in IJOP. However, they grant the journal an exclusive Creative Commons license.
Creative Commons License: The authors grant IJOP the right to exclusively apply a Creative Commons license to their work upon publication. This license permits use, distribution, and reproduction of the work in any medium, provided that the original work and its source are properly cited. The specific license applied is Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0), which allows for attribution, non-commercial use, and derivative works.
Editorial Research: Authors grant the journal the right to analyze information obtained from submitted manuscripts for editorial research purposes. This analysis aims to improve the peer-review process, teaching, and training activities.
Warranties: Authors warrant that their work is original, contains no libelous statements, is lawful, and does not infringe upon any copyright, trademark, patent, or proprietary rights of others. Authors agree to indemnify the editors against any costs, expenses, and damages arising from any breach of this warranty.
Views and Opinions: The views and opinions expressed in the article are those of the authors and not necessarily those of the journal.