A Rare Case Report: The Unusual Combination of Dermoid Cyst and Cystadenoma in Ovarian Collision Tumors

Abstract

Collision tumors, the coexistence of two distinct neoplasms in the same tissue without histological admixture, are rare, particularly in the ovary. This report documents an unusual case of a 50-year-old postmenopausal woman who presented with a 4-month history of lower abdominal pain and distention. Imaging and surgical findings revealed a large right ovarian mass, which histopathology identified as a mucinous cystadenoma coexisting with a benign cystic teratoma. This rare combination underscores the importance of considering collision tumors in differential diagnoses of ovarian masses. Molecular studies suggest a potential clonal relationship, with shared genetic changes supporting a teratomatous origin for mucinous tumors. This case contributes to the limited literature on ovarian collision tumors, emphasizing the need for awareness and accurate diagnosis of these rare entities to guide appropriate treatment strategies.